At it's most serious, the message "System Software Missing" can indicate physical flash damage involving the region containing the firmware [Garmin calls it 'system software']. Mostly it's less insidious and only means data in the firmware region [rgn14] has become corrupt or has been erased in which case that's easily fixed by reflashing.
The error message you've got from Updater.exe is concerning if you've tried multiple times to flash and have used different USB cables, different USB ports or even another PC. Note: Use only directly connected [no hub] rear USB2 ports of the PC, not USB3.
If you've tried all the above then please post a link to the firmware you're using, maybe we can try something else.
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