This information is not much to go on. You (and thus we) don't know what program, nor how it is installed, what is installed internally (flash memory) or externally (SD).
We don't know what device and must guess it's a Windows CE Operating system.
How do you start your program? Is there a shell or does IGO start from Windows home screen or automatically? When you try to start it now using no SD or the broken one, what is the error message? I hope you understand that "the program is not found" needs a different approach from "the maps are not found".
And last for now: some information about your device could help us what IGO or Primo to consider when you need a new install