It is not a question of screen ratio, the software does not care. It is only necessary to define the resolution, it will work on any screen with the given resolution.
Even an old versions of Primo's worked great on 4:3, also on every other. I always recommended "Explay Infinity I & II" editions, because their packages always led all the necessary information only (for example: 1280x720, 1024x768, 800x600, etc).
For newer devices, it is advisable to use the latest versions because they are adapted to high resolutions (> HD) and to some other things. Because they require a little more knowledge and skills about the settings, you should not be lazy and find out and learn something from these forum. Read and learn.